Wim Degrave - DBBM FIOCRUZ
David C. Martin - IBM Life Sciences
What is in a genome? Coding and non-coding sequences, by Wim Degrave
Many prokaryotic and eukaryotic genomes have been fully sequenced, and
almost all of the attention has been drawn to protein-coding regions, in
the search for new drug, vaccine and diagnostic targets, and as a focal
point of study in evolutionary biology. Annotation systems are also
designed mainly to uncover and detail protein-coding sequences.
Relatively little is known about the structure and function of
non-coding regions, repetitive DNA, and control regions for gene
expression and chromosome structure and function, which remains a
challenge for analysis and annotation systems.
Wim Degrave has a degree in Chemistry and Ph.D. in Molecular Biology,
both from the Federal University of Gent, Bélgium. Since 1985 he is
active in the Department for Biochemistry and Molecular Biology, Oswaldo
Cruz Institute . Fiocruz, as senior researcher and head of the
Laboratory for Functional Genomics and Bioinformatics. Since 1987, he is
responsible for bioinformatics at Fiocruz, having organized several
post-graduate, regional and international courses in this field. He is
coordinator of the Latin-American and Caribbean Network for
Bioinformatics (LacBioNet) and for the Ibero-American network for
Bioinformatics (RIBio)
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Information Integration Practices for Bioinformatics, by David Martin
IBM Life Sciences has assisted leading institutions in the development of
bioinformatics solutions. This presentation will highlight some of these
engagements, including the Mayo Clinic, Indiana University and Johns
Hopkins University.
Executive Biography
David C. Martin is Program Executive for Integrated Industry Solutions in
IBM Life Sciences Solutions. Previously, he led the research and
development of data mining and customer relationship management solutions
for IBM at the Almaden Research Center and Austin Development Lab,
including the development of DecisionEdge, IntelligentMiner and SurfAid. He
has also worked at University of California at San Francisco, and as a
Senior Scientist for Molecular Simulations. David holds six patents,
including the Web browser plug-in (US 5838906), a B.A. from the University
of California at Berkeley and an M.S. in computer science from the
University of Wisconsin at Madison.
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